Synthesis of monodisperse biodegradable microgels in microfluidic devices.
نویسندگان
چکیده
Microgels are promising materials in drug delivery and biomedicine. Although monodisperse microgels would offer considerable advantages, most microgels investigated and used today are polydisperse in size. We report on the fabrication of 10 mum sized monodisperse microgels by emulsifying an aqueous dextran-hydroxyethyl methacrylate (dex-HEMA) phase within an oil phase at the junction of microfluidic channels. Dex-HEMA microgels are biodegradable and are ideally suited for the controlled delivery of proteins.
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ورودعنوان ژورنال:
- Langmuir : the ACS journal of surfaces and colloids
دوره 21 23 شماره
صفحات -
تاریخ انتشار 2005